With the trend of integrating the world and regional economy, financial markets have expanded strongly, especially capital markets. Moreover, the International Accounting Standards (IAS/IFRS) have become a global language in the preparing and presenting of financial statements. The objective of this chapter is to examine the macro factors affecting the adoption of IAS/IFR in Vietnam. The authors use mixed methods based on logarithm models with secondary data of 147 countries to examine the following factors: culture, economic growth, capital markets, education, foreign operation, law, and politics. The authors propose implications of promoting the process of IAS/IFRS adoption in the country.