Factors associate with adherence to anti - hypertensive treatment among essential hypertensive patients

Abstract

This research is to determine the factors associate with adherence to anti-hypertensive treatment among essential hypertensive patients”. A cross-sectional research was carried out on 164 essential hypertensive patients older than 25 years, treated at least one month. An adjusted Questionnaire was designed to interview patients. Adherence was evaluated by two models: MMAS-8 –DMMAS with score ≥ 6; Pill counting – NEWADH with rate of anti-hypertensive medication taken correctly during two last week > 80%. Data were analyzed with STATA program using percentage, mean value, standard deviation, Breusch – Pagan/ Cook-Weisbergtest for test of heteroskedasticity and VIF for multicollinearity test. The rate of adherence in both models of MMAS-8 (DMMAS) and Pill-counting (NEWADH) were respectively found 127 (77.4%) and 147 (91.3%). Pill-counting showed association between adherence and factors of age, married, college or university, gender, retied, treatment expenses paid by insurance or supported by family, income, number of taken anti-hypertensive drugs and medication side effect. In conclusion, factors of socio-demographics and complex of anti-hypertensive drug regimens impact adherence of patients. The negative association between adherence and complex of anti-hypertensive drug regimens including number of taken anti-hypertensive drugs and drug side effects suggests interplay of other factors and needs further research.