The dynamic growth of a supply chain in an incessantly changing environment emanates from the dynamics of an organisation as well as its supply chain members. The primary aim of this research is to investigate the relationships between supply chain agility and its dynamic precursors including organisational ambidexterity and external knowledge sharing. The research further examines the moderating role of competitive intelligence for the relationship between organisational ambidexterity and supply chain agility. A sample of 381 respondents from chemical manufacturing companies in Vietnam produced the data for analysis. The research results shed light on the chain effect from organisational ambidexterity through external knowledge sharing to supply chain agility. The moderating role that CI plays in the relationship between organisational ambidexterity and supply chain agility was also verified. The findings from the research broaden supply chain literature through establishing the positive effect of organisational ambidexterity on supply chain agility with CI as a moderator for this effect.